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| Yohimbine-HCl |
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| Yohimbine is an Indole alkaloid. It is white to slightly yellow crystalline powder . Its chemical formula is 17α-Hydroxy-20-α-yohimban-16-β-carboxylic acid, methyl ester, hydrochloride and its molecular formula is C21H26N2O3.HCl. |
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| Yohimbine is used both as an over-the-counter dietary supplement in herbal extract form and prescription medicine in pure form for the treatment of sexual dysfunction(E.D.). Yohimbine was recently associated as a remedy for type 2 diabetes mellitus. |
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| Source |
| Yohimbine is the principal alkaloid of the bark of the West African evergreen Pausinystalia yohimbe (formerly Corynanthe yohimbe), family Rubiaceae (Madder family). There are 31 other yohimbine alkaloids found in Yohimbe. In Africa, yohimbe has traditionally been used as an aphrodisiac. |
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| The main active chemical present in yohimbe bark is yohimbine HCl . |
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| Pharmacology |
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| Yohimbe is one of the most popular supplement for years. When ingested, the body converts it to yohimbine and assimilates it into the bloodstream. |
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| The active alkaloid, yohimbine bitartrate, is the component of the only allopathic medicines known to cause erection in impotent males and approaches the concept of an aphrodisiac. Yohimbine bitartrate particularly affects nerves and changes blood flow regulators in the genital area. |
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| Yohimbe bark stimulates chemical reactions in the body that may aid in psychogenic cases of impotence, due to fatigue, tension and stress. Clinical studies have shown the herb to be effective in restoring potency in diabetic and heart patients who suffer from impotency. |
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| Therapeutic Application |
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- Yohimbine Hydrochloride is a prescription medicine to treat erectile dysfunction.
- Yohimbine is also effective in the treatment of orgasmic dysfunction in men.
- Yohimbine has also been used for the treatment of sexual side effects caused by some antidepressants (SSRIs), female hyposexual disorder, as a blood pressure boosting agent in autonomic failure, xerostomia, and as a probe for noradrenergic activity.
- Oral yohimbine supplementation may actuate significant fat loss in athletes.
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| Dosage |
| The usual dose of Yohimbine is 30 mg a day (two 5 mg tablets three times daily) for eight weeks. |
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